Back to Search
Start Over
Stratification of peanut allergic murine model into anaphylaxis severity risk groups using thermography.
- Source :
-
Journal of immunological methods [J Immunol Methods] 2018 Aug; Vol. 459, pp. 29-34. Date of Electronic Publication: 2018 May 23. - Publication Year :
- 2018
-
Abstract
- Murine models are readily used to investigate mechanisms potentially involved in anaphylaxis. Determining successful sensitization with current methods remain potentially lethal, invasive, expensive and/or cumbersome. Here we describe the use of thermography to read intradermal testing to detect peanut allergic sensitization in the murine model and as a first time sensitive tool for anaphylaxis stratification. The relative wheal size in the thermal image can be used to stratify anaphylaxis severity risk groups prior to a challenge. This screening method is nonlethal, inexpensive, minimally invasive and can be carried out expeditiously.<br /> (Copyright © 2018 Elsevier B.V. All rights reserved.)
- Subjects :
- Allergens
Animals
Disease Models, Animal
Female
Histamine administration & dosage
Intradermal Tests methods
Mice
Severity of Illness Index
Urticaria chemically induced
Urticaria immunology
Anaphylaxis diagnosis
Arachis immunology
Peanut Hypersensitivity diagnosis
Thermography methods
Urticaria diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1872-7905
- Volume :
- 459
- Database :
- MEDLINE
- Journal :
- Journal of immunological methods
- Publication Type :
- Academic Journal
- Accession number :
- 29802879
- Full Text :
- https://doi.org/10.1016/j.jim.2018.05.003