Back to Search
Start Over
Effect of methicillin-resistant Staphylococcus aureus in Japan.
- Source :
-
American journal of infection control [Am J Infect Control] 2018 Oct; Vol. 46 (10), pp. 1142-1147. Date of Electronic Publication: 2018 May 18. - Publication Year :
- 2018
-
Abstract
- Background: Methicillin-resistant Staphylococcus aureus (MRSA) is the most common antimicrobial-resistant organism identified in Japanese health care facilities. This study analyzed the clinical and economic burdens attributable to methicillin resistance in S aureus in Japanese hospitals.<br />Methods: We retrospectively investigated data from 14,905 inpatients of 57 hospitals combined with data from nosocomial infection surveillance and administrative claim databases. The participants were inpatients with admission from April 1, 2014, to discharge on March 31, 2016. The outcomes were evaluated according to length of stay, hospital charges, and in-hospital mortality. We compared the disease burden of MRSA infections with methicillin-susceptible S aureus (MSSA) infections based on patients' characteristics and onset periods.<br />Results: We categorized 7,188 and 7,717 patients into MRSA and MSSA groups, respectively. The adjusted effects of the MRSA group were 1.03-fold (95% confidence interval [CI] 1.01-1.05) and 1.04-fold (95% CI, 1.01-1.06), respectively, with an odds ratio of 1.14 (95% CI, 1.02-1.27).<br />Conclusions: The results of this study found that patient severity and onset delays were positively associated with both MRSA and burden and that the effect of methicillin resistance remained significant after adjustment.<br /> (Copyright © 2018. Published by Elsevier Inc.)
- Subjects :
- Adult
Aged
Aged, 80 and over
Anti-Bacterial Agents economics
Anti-Bacterial Agents therapeutic use
Cross Infection drug therapy
Cross Infection economics
Female
Humans
Japan epidemiology
Male
Methicillin pharmacology
Methicillin Resistance
Middle Aged
Cross Infection microbiology
Health Care Costs
Hospitalization economics
Methicillin-Resistant Staphylococcus aureus
Staphylococcal Infections epidemiology
Staphylococcal Infections microbiology
Subjects
Details
- Language :
- English
- ISSN :
- 1527-3296
- Volume :
- 46
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- American journal of infection control
- Publication Type :
- Academic Journal
- Accession number :
- 29784441
- Full Text :
- https://doi.org/10.1016/j.ajic.2018.04.214