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Van Wyk Grumbach Syndrome: A Rare Consequence of Hypothyroidism.
- Source :
-
Indian journal of pediatrics [Indian J Pediatr] 2018 Nov; Vol. 85 (11), pp. 1028-1030. Date of Electronic Publication: 2018 May 19. - Publication Year :
- 2018
-
Abstract
- Long standing hypothyroidism presenting as an ovarian mass has been well described in literature as the Van Wyk Grumbach syndrome (hypothyroidism, isosexual precocious puberty and ovarian mass). Here, authors report this entity in a 11 y 7 mo old girl child who was referred to a surgeon in view of intestinal obstruction along with a multiloculated ovarian cyst. On evaluation, she was found to have raised serum creatinine, short stature, delayed bone age and pituitary enlargement. She was diagnosed with autoimmune thyroiditis and was started on replacement therapy with thyroxine, after which the ovarian cysts regressed. This entity should be kept in mind in cases of ovarian cysts, especially those with isosexual precocity, to prevent unnecessary evaluation and surgical misadventures.
- Subjects :
- Child
Female
Hormone Replacement Therapy
Humans
Hypothyroidism complications
Intestinal Obstruction complications
Ovarian Cysts complications
Puberty, Precocious complications
Syndrome
Thyroiditis, Autoimmune complications
Thyroiditis, Autoimmune drug therapy
Thyroxine therapeutic use
Hypothyroidism diagnosis
Ovarian Cysts diagnosis
Puberty, Precocious diagnosis
Thyroiditis, Autoimmune diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 0973-7693
- Volume :
- 85
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Indian journal of pediatrics
- Publication Type :
- Academic Journal
- Accession number :
- 29777468
- Full Text :
- https://doi.org/10.1007/s12098-018-2704-2