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A Randomized, Placebo-Controlled Study on the Safety and Efficacy of Daily Ingestion of Green Tea ( Camellia sinensis L.) cv. "Yabukita" and "Sunrouge" on Eyestrain and Blood Pressure in Healthy Adults.
- Source :
-
Nutrients [Nutrients] 2018 May 06; Vol. 10 (5). Date of Electronic Publication: 2018 May 06. - Publication Year :
- 2018
-
Abstract
- The green tea ( Camellia sinensis L.) cultivar &ldquo;Sunrouge&rdquo; contains anthocyanins, catechins and flavonols. To determine whether ingesting green tea containing anthocyanins improves visual function and blood pressure (BP) in healthy adults, a randomized, double-blind, placebo-controlled study was performed. A total of 120 healthy subjects, aged between 20 and 60 years and with a systolic BP (SBP) value of &le;125 and <155 and a diastolic BP (DBP) value <95, or a DBP of &le;75 mmHg and <95 mmHg and a SBP <155 mmHg, were randomly assigned to one of three groups. For 12 weeks, the placebo group received barley extract without catechin; another group received &ldquo;Sunrouge&rdquo; extract containing 11.2 mg anthocyanin and 323.6 mg epigallocatechin-3- O -gallate (EGCG); and a third group received &ldquo;Yabukita&rdquo; extract containing 322.2 mg EGCG. Home BP, accommodation ability, visual analog scale questionnaires for eyestrain, and metabolic-associated markers were analyzed at weeks 0, 4, 8, and 12 of the intake period. The ingestion of &ldquo;Sunrouge&rdquo; tea significantly improved accommodation ability and eyestrain in subjects younger than 45 years and in subjects who operated visual display terminals every day. It also elevated BP. &ldquo;Yabukita&rdquo; tea ingestion significantly increased serum adiponectin levels. No adverse effects were observed. We conclude that long-term intake of &ldquo;Sunrouge&rdquo; tea containing anthocyanins and flavonols might improve visual function.
- Subjects :
- Accommodation, Ocular drug effects
Adult
Anthocyanins pharmacology
Asthenopia diagnosis
Catechin analogs & derivatives
Catechin pharmacology
Catechols pharmacology
Double-Blind Method
Female
Flavonols pharmacology
Humans
Male
Middle Aged
Plant Extracts pharmacology
Plant Leaves chemistry
Surveys and Questionnaires
Treatment Outcome
Visual Analog Scale
Young Adult
Asthenopia drug therapy
Asthenopia prevention & control
Blood Pressure drug effects
Diet
Tea chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 2072-6643
- Volume :
- 10
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Nutrients
- Publication Type :
- Academic Journal
- Accession number :
- 29734777
- Full Text :
- https://doi.org/10.3390/nu10050569