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Intradiscal ozone therapy for lumbar disc herniation.
- Source :
-
Cellular and molecular biology (Noisy-le-Grand, France) [Cell Mol Biol (Noisy-le-grand)] 2018 Apr 30; Vol. 64 (5), pp. 52-55. Date of Electronic Publication: 2018 Apr 30. - Publication Year :
- 2018
-
Abstract
- The rationale behind intradiscal O2-O3 therapy is the pain elicited by the mechanical compression of the nerve root, which is associated with periganglionic and periradicular inflammation. This study aimed to determine the effect of intradiscal ozone injection on pain score and satisfaction of patients with low back pain (LBP) secondary to disc herniation. Patients with LBP diagnosed with disc herniation were enrolled in this clinical trial. After prepping and draping the area, intradiscal injection of ozone/oxygen mixture (10 ml, 25μg/ml) was performed under fluoroscopy guide (c-arm). Pain score and patient satisfaction were assessed prior to the injection (baseline) and 1, 3, 6, 12 and 24 months after the injection. Sixty three patients (24 males, 39 females) with mean age of 53.3 ±2.0 y enrolled in the study. The mean±standard deviation (SD) of pain score before intervention was 6.968 ±0.11. Pain score was reduced to 4.25±0.19 at 1 month, 4.33±0.20 at 3 months, 4.87 ±0.21 at 6 months and 5.22 ±0.20 at 24 months. According to the modified MacNab scale success of pain relief was as follows: excellent: 4 (6.3%), good: 17 (26.98 %), sufficient: 13 (20.63 %), poor: 13 (20.63 %), no result: 11 (17.46%), negative: 4 (6.3 %). Intradiscal ozone therapy was determined to provide improved outcomes in patients with single level of bulging and protrusion.
- Subjects :
- Female
Fluoroscopy
Humans
Injections, Intralesional
Intervertebral Disc diagnostic imaging
Intervertebral Disc drug effects
Intervertebral Disc innervation
Intervertebral Disc pathology
Intervertebral Disc Displacement diagnostic imaging
Intervertebral Disc Displacement pathology
Low Back Pain diagnostic imaging
Low Back Pain pathology
Lumbar Vertebrae diagnostic imaging
Lumbar Vertebrae drug effects
Lumbar Vertebrae innervation
Lumbar Vertebrae pathology
Male
Middle Aged
Pain Measurement statistics & numerical data
Patient Satisfaction statistics & numerical data
Treatment Outcome
Anti-Inflammatory Agents, Non-Steroidal therapeutic use
Intervertebral Disc Displacement drug therapy
Low Back Pain drug therapy
Oxygen therapeutic use
Ozone therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1165-158X
- Volume :
- 64
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Cellular and molecular biology (Noisy-le-Grand, France)
- Publication Type :
- Academic Journal
- Accession number :
- 29729693