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Executive functioning and central coherence in anorexia nervosa: Pilot investigation of a neurocognitive endophenotype.
- Source :
-
European eating disorders review : the journal of the Eating Disorders Association [Eur Eat Disord Rev] 2018 Sep; Vol. 26 (5), pp. 489-498. Date of Electronic Publication: 2018 Apr 27. - Publication Year :
- 2018
-
Abstract
- A neurocognitive profile characterized by problems in set shifting, executive functioning, and central coherence may pre-date and maintain anorexia nervosa (AN). To test this pattern as a possible endophenotype for AN, 10 youth with current AN, 14 healthy youth, and their biological parents, participated in a neuropsychological battery. Youth with AN demonstrated significantly weaker central coherence, related to enhanced detail-focused processing. Youth with AN and their parents demonstrated significantly greater psychopathology relative to controls, and youth-parent scores were significantly correlated. The study, limited by a small sample size, found little evidence supporting a neuropsychological endophenotype for AN. Identifying a neurocognitive profile for children and adolescents with AN has important implications for the treatment of young patients.<br /> (Copyright © 2018 John Wiley & Sons, Ltd and Eating Disorders Association.)
- Subjects :
- Adolescent
Adult
Anorexia Nervosa diagnosis
Anorexia Nervosa psychology
Anorexia Nervosa therapy
Case-Control Studies
Child
Cognition Disorders physiopathology
Female
Humans
Male
Pilot Projects
Anorexia Nervosa genetics
Cognition Disorders diagnosis
Cognition Disorders genetics
Cognition Disorders psychology
Endophenotypes
Executive Function physiology
Neuropsychological Tests statistics & numerical data
Subjects
Details
- Language :
- English
- ISSN :
- 1099-0968
- Volume :
- 26
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- European eating disorders review : the journal of the Eating Disorders Association
- Publication Type :
- Academic Journal
- Accession number :
- 29700970
- Full Text :
- https://doi.org/10.1002/erv.2597