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Prospective Observational Study on acute Appendicitis Worldwide (POSAW).

Authors :: Sartelli M
Baiocchi GL
Di Saverio S
Ferrara F
Labricciosa FM
Ansaloni L
Coccolini F
Vijayan D
Abbas A
Abongwa HK
Agboola J
Ahmed A
Akhmeteli L
Akkapulu N
Akkucuk S
Altintoprak F
Andreiev AL
Anyfantakis D
Atanasov B
Bala M
Balalis D
Baraket O
Bellanova G
Beltran M
Melo RB
Bini R
Bouliaris K
Brunelli D
Castillo A
Catani M
Che Jusoh A
Chichom-Mefire A
Cocorullo G
Coimbra R
Colak E
Costa S
Das K
Delibegovic S
Demetrashvili Z
Di Carlo I
Kiseleva N
El Zalabany T
Faro M
Ferreira M
Fraga GP
Gachabayov M
Ghnnam WM
Giménez Maurel T
Gkiokas G
Gomes CA
Griffiths E
Guner A
Gupta S
Hecker A
Hirano ES
Hodonou A
Hutan M
Ioannidis O
Isik A
Ivakhov G
Jain S
Jokubauskas M
Karamarkovic A
Kauhanen S
Kaushik R
Kavalakat A
Kenig J
Khokha V
Khor D
Kim D
Kim JI
Kong V
Lasithiotakis K
Leão P
Leon M
Litvin A
Lohsiriwat V
López-Tomassetti Fernandez E
Lostoridis E
Maciel J
Major P
Dimova A
Manatakis D
Marinis A
Martinez-Perez A
Marwah S
McFarlane M
Mesina C
Pędziwiatr M
Michalopoulos N
Misiakos E
Mohamedahmed A
Moldovanu R
Montori G
Mysore Narayana R
Negoi I
Nikolopoulos I
Novelli G
Novikovs V
Olaoye I
Omari A
Ordoñez CA
Ouadii M
Ozkan Z
Pal A
Palini GM
Partecke LI
Pata F
Pędziwiatr M
Pereira Júnior GA
Pintar T
Pisarska M
Ploneda-Valencia CF
Pouggouras K
Prabhu V
Ramakrishnapillai P
Regimbeau JM
Reitz M
Rios-Cruz D
Saar S
Sakakushev B
Seretis C
Sazhin A
Shelat V
Skrovina M
Smirnov D
Spyropoulos C
Strzałka M
Talving P
Teixeira Gonsaga RA
Theobald G
Tomadze G
Torba M
Tranà C
Ulrych J
Uzunoğlu MY
Vasilescu A
Occhionorelli S
Venara A
Vereczkei A
Vettoretto N
Vlad N
Walędziak M
Yilmaz TU
Yuan KC
Yunfeng C
Zilinskas J
Grelpois G
Catena F
Source :: World journal of emergency surgery : WJES [World J Emerg Surg] 2018 Apr 16; Vol. 13, pp. 19. Date of Electronic Publication: 2018 Apr 16 (Print Publication: 2018).
Publication Year :: 2018
Abstract: Background: Acute appendicitis (AA) is the most common surgical disease, and appendectomy is the treatment of choice in the majority of cases. A correct diagnosis is key for decreasing the negative appendectomy rate. The management can become difficult in case of complicated appendicitis. The aim of this study is to describe the worldwide clinical and diagnostic work-up and management of AA in surgical departments.<br />Methods: This prospective multicenter observational study was performed in 116 worldwide surgical departments from 44 countries over a 6-month period (April 1, 2016-September 30, 2016). All consecutive patients admitted to surgical departments with a clinical diagnosis of AA were included in the study.<br />Results: A total of 4282 patients were enrolled in the POSAW study, 1928 (45%) women and 2354 (55%) men, with a median age of 29 years. Nine hundred and seven (21.2%) patients underwent an abdominal CT scan, 1856 (43.3%) patients an US, and 285 (6.7%) patients both CT scan and US. A total of 4097 (95.7%) patients underwent surgery; 1809 (42.2%) underwent open appendectomy and 2215 (51.7%) had laparoscopic appendectomy. One hundred eighty-five (4.3%) patients were managed conservatively. Major complications occurred in 199 patients (4.6%). The overall mortality rate was 0.28%.<br />Conclusions: The results of the present study confirm the clinical value of imaging techniques and prognostic scores. Appendectomy remains the most effective treatment of acute appendicitis. Mortality rate is low.<br />Competing Interests: The data was completely anonymized, and no patient or hospital information was collected in the database. The study protocol was approved by the board of the WSES, and the study was conducted under its supervision. The board of the WSES grants the proper ethical conduct of the study.The authors declare that they have no competing interests.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.