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Dietary Supplementation with Pioglitazone Hydrochloride and Chromium Methionine Improves Growth Performance, Meat Quality, and Antioxidant Ability in Finishing Pigs.
- Source :
-
Journal of agricultural and food chemistry [J Agric Food Chem] 2018 May 02; Vol. 66 (17), pp. 4345-4351. Date of Electronic Publication: 2018 Apr 23. - Publication Year :
- 2018
-
Abstract
- This work was designed to investigate the synergistic effects of pioglitazone hydrochloride (PGZ) and chromium methionine (CrMet) on meat quality, muscle fatty acid profile, and antioxidant ability of pigs. Pigs in four groups were fed a basic diet or basic diet supplemented with 15 mg/kg of PGZ, 200 μg/kg of CrMet, or 15 mg/kg of PGZ + 200 μg/kg of CrMet. In comparison to the control group, the average daily feed intake, feed/gain ratio, and serum high-density lipoprotein level decreased in the PGZ + CrMet group. Dietary PGZ + CrMet supplementation increased carcass dressing percentage, intramuscular fat, and marbling score. The percentages of C18:1ω-9c, C18:2ω-6c, C18:3ω-3, and polyunsaturated fatty acid (PUFA) in the longissimus thoracis muscle were increased in the PGZ + CrMet group. Greater superoxide dismutase and glutathione peroxidase activities were observed in the PGZ + CrMet group compared to the control group. Collectively, these findings suggested that feed with PGZ and CrMet improved the growth performance and meat quality, especially for PUFA proportions and antioxidant ability.
- Subjects :
- Adipose Tissue
Animal Feed
Animals
Antioxidants analysis
Body Composition drug effects
Dietary Supplements
Drug Synergism
Fatty Acids analysis
Female
Lipoproteins, HDL blood
Male
Muscle, Skeletal chemistry
Muscle, Skeletal physiology
Pioglitazone
Chromium administration & dosage
Diet veterinary
Meat analysis
Methionine administration & dosage
Sus scrofa growth & development
Thiazolidinediones administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 1520-5118
- Volume :
- 66
- Issue :
- 17
- Database :
- MEDLINE
- Journal :
- Journal of agricultural and food chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 29682966
- Full Text :
- https://doi.org/10.1021/acs.jafc.8b01176