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Comparison of the adverse events of anterior cervical disc replacement versus anterior cervical discectomy and fusion: A protocol for a systematic review and meta-analysis of prospective randomized controlled trials.
- Source :
-
Medicine [Medicine (Baltimore)] 2018 Apr; Vol. 97 (16), pp. e0015. - Publication Year :
- 2018
-
Abstract
- Background: In the current surgical therapeutic regimen for symptomatic cervical degenerative disc disease, both anterior cervical discectomy and fusion (ACDF) and anterior cervical disc replacement (ACDR) are still widely accepted. However, many complications exist in both surgeries. Therefore, this study aims to compare the adverse events between ACDR and ACDF, and provide vital evidence-based guidance for spine surgeons and designers to evaluation of prognosis and improvement of dynamic devices.<br />Methods: A systematic review and meta-analysis that will be performed according to the PRISMA. The electric database of PubMed, Medline, Embase, Google Scholar, and Cochrane library will be systematic search. A standard data form will be used to extract the data of included studies. We will assess the studies according to the Cochrane Handbook for Systematic Reviews of Interventions, and perform analysis in RevMan 5.3 software. Fixed effects models will be used for homogeneity data, while random-effects will be used for heterogeneity data. The overall effect sizes will be determined as weighted mean difference (WMD) for continuous outcomes and relative risk (RR) for dichotomous outcomes.<br />Result: The results of this study will be disseminated via international or national conferences, or submit to peer-reviewed journal in spinal field.<br />Conclusion: The conclusion of this study will provide key evidence-based guidance for spine surgeons and designers to the evaluation of prognosis and improvement of dynamic devices.
- Subjects :
- Humans
Intervertebral Disc Degeneration diagnosis
Outcome and Process Assessment, Health Care
Randomized Controlled Trials as Topic
Research Design
Risk Assessment methods
Cervical Vertebrae pathology
Cervical Vertebrae surgery
Diskectomy adverse effects
Diskectomy methods
Intervertebral Disc Degeneration surgery
Postoperative Complications diagnosis
Postoperative Complications etiology
Postoperative Complications prevention & control
Spinal Fusion adverse effects
Spinal Fusion methods
Total Disc Replacement adverse effects
Total Disc Replacement methods
Subjects
Details
- Language :
- English
- ISSN :
- 1536-5964
- Volume :
- 97
- Issue :
- 16
- Database :
- MEDLINE
- Journal :
- Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 29668575
- Full Text :
- https://doi.org/10.1097/MD.0000000000010015