Bioinformatics-guided connection of a biosynthetic gene cluster to the antitumor antibiotic gilvusmycin.

Authors :: Wang X
Wu S
Jin W
Xu B
Tang G
Yuan H
Source :: Acta biochimica et biophysica Sinica [Acta Biochim Biophys Sin (Shanghai)] 2018 May 01; Vol. 50 (5), pp. 516-518.
Publication Year :: 2018

Subjects :: Antibiotics, Antineoplastic chemistry
Bacterial Proteins metabolism
Biological Products chemistry
Biological Products metabolism
Drug Screening Assays, Antitumor
Duocarmycins
Indoles chemistry
Indoles metabolism
Molecular Structure
Streptomyces metabolism
Antibiotics, Antineoplastic biosynthesis
Bacterial Proteins genetics
Biosynthetic Pathways genetics
Computational Biology methods
Genes, Bacterial genetics
Streptomyces genetics

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