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[Bushen Daozhuo Granules for type Ⅲ prostatitis: A multicenter randomized controlled clinical trial].
- Source :
-
Zhonghua nan ke xue = National journal of andrology [Zhonghua Nan Ke Xue] 2017 Feb; Vol. 23 (2), pp. 164-168. - Publication Year :
- 2017
-
Abstract
- Objective: To study the safety and efficacy of Bushen Daozhuo Granules (BDG) in the treatment of type Ⅲ prostatitis.<br />Methods: This multicenter randomized controlled clinical trial included 478 patients with type Ⅲ prostatitis, 290 in the trial group and 188 as controls, the former treated with BDG at 200 ml bid and the latter with tamsulosin hydrochloride sustainedrelease capsules at 0.2 mg qd, both for 4 weeks. Before treatment, after 4 weeks of medication, and at 4 weeks after drug withdrawal, we obtained the NIH Chronic Prostatitis Symptom Index (NIHCPSI) scores and compared the safety and effectiveness rate between the two groups of patients.<br />Results: Compared with the baseline, the NIHCPSI score was markedly decreased in the control group after 4 weeks of medication (21.42 ± 4.02 vs 15.67 ± 3.65, P < 0.05) but showed no statistically significant difference from that at 4 weeks after drug withdrawal (19.03 ± 3.86) (P>0.05), while the NIHCPSI score in the trial group was remarkably lower than the baseline both after 4 weeks of medication and at 4 weeks after drug withdrawal (10.92 ± 2.06 and 12.91 ± 2.64 vs 21.58 ± 3.67, P < 0.05). The trial group exhibited both a higher rate of total effectiveness and safety than the control (P < 0.05).<br />Conclusions: BDG is safe and effective for the treatment of type Ⅲ prostatitis.
- Subjects :
- Capsules
Chronic Disease
Delayed-Action Preparations
Drugs, Chinese Herbal adverse effects
Humans
Male
Prostatitis pathology
Sulfonamides adverse effects
Sulfonamides therapeutic use
Tamsulosin
Treatment Outcome
Urological Agents adverse effects
Drugs, Chinese Herbal therapeutic use
Prostatitis drug therapy
Urological Agents therapeutic use
Subjects
Details
- Language :
- Chinese
- ISSN :
- 1009-3591
- Volume :
- 23
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Zhonghua nan ke xue = National journal of andrology
- Publication Type :
- Academic Journal
- Accession number :
- 29658256