Analysis on the emission and potential application of Cherenkov radiation in boron neutron capture therapy: A Monte Carlo simulation study.

Authors :: Shu DY
Geng CR
Tang XB
Gong CH
Shao WC
Ai Y
Source :: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine [Appl Radiat Isot] 2018 Jul; Vol. 137, pp. 219-224. Date of Electronic Publication: 2018 Apr 06.
Publication Year :: 2018
Abstract: This paper was aimed to explore the physics of Cherenkov radiation and its potential application in boron neutron capture therapy (BNCT). The Monte Carlo toolkit Geant4 was used to simulate the interaction between the epithermal neutron beam and the phantom containing boron-10. Results showed that Cherenkov photons can only be generated from secondary charged particles of gamma rays in BNCT, in which the 2.223 MeV prompt gamma rays are the main contributor. The number of Cherenkov photons per unit mass generated in the measurement region decreases linearly with the increase of boron concentration in both water and tissue phantom. The work presented the fundamental basis for applications of Cherenkov radiation in BNCT.<br /> (Copyright © 2018 Elsevier Ltd. All rights reserved.)

Subjects :: Biophysical Phenomena
Boron
Boron Neutron Capture Therapy statistics & numerical data
Computer Simulation
Humans
Isotopes
Monte Carlo Method
Neutrons
Phantoms, Imaging
Photons
Boron Neutron Capture Therapy methods

Language :: English
ISSN :: 1872-9800
Volume :: 137
Database :: MEDLINE
Journal :: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
Publication Type :: Academic Journal
Accession number :: 29655128
Full Text :: https://doi.org/10.1016/j.apradiso.2018.04.012

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