Clonal genetic evolution at relapse of favorable-risk acute myeloid leukemia with NPM1 mutation is associated with phenotypic changes and worse outcomes.

Subjects

Subjects :

Biomarkers, Tumor
DNA Mutational Analysis
Genetic Association Studies
Genome-Wide Association Study
Humans
Leukemia, Myeloid, Acute mortality
Nucleophosmin
Prognosis
Recurrence
Clonal Evolution genetics
Leukemia, Myeloid, Acute diagnosis
Leukemia, Myeloid, Acute genetics
Mutation
Nuclear Proteins genetics
Phenotype

Details

Language :

English

ISSN :

1592-8721

Volume :

103

Issue :

9

Database :

MEDLINE

Journal :

Haematologica

Publication Type :

Report

Accession number :

29622659

Full Text :

https://doi.org/10.3324/haematol.2018.188433