A novel biphenyl-derived salicylhydrazone Schiff base fluorescent probes for identification of Cu 2+ and application in living cells.

Authors :: Yang YS
Ma SS
Zhang YP
Ru JX
Liu XY
Guo HC
Source :: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2018 Jun 15; Vol. 199, pp. 202-208. Date of Electronic Publication: 2018 Mar 24.
Publication Year :: 2018
Abstract: A novel biphenyl-derived salicylhydrazone Schiff base (BSS) fluorescent probes for highly sensitive and selective identification of Cu <superscript>2+</superscript> has been synthesized. In addition, the recognition has been proved experimentally. The results indicated that the complex forms a 1:1 complex with Cu <superscript>2+</superscript> shows fluorescent quenching. Furthermore, the detection limit of 1.54×10 <superscript>-8</superscript> M. More interesting, the probe BSS not only have a good biocompatibility in living cells, but also the sense behavior of Cu <superscript>2+</superscript> in the cell nucleus.<br /> (Copyright © 2018 Elsevier B.V. All rights reserved.)

Subjects :: HeLa Cells
Humans
Limit of Detection
Spectrometry, Fluorescence
Biphenyl Compounds chemistry
Copper analysis
Fluorescent Dyes chemistry
Hydrazones chemistry
Salicylates chemistry
Schiff Bases chemistry

Language :: English
ISSN :: 1873-3557
Volume :: 199
Database :: MEDLINE
Journal :: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Publication Type :: Academic Journal
Accession number :: 29605784
Full Text :: https://doi.org/10.1016/j.saa.2018.03.060

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