Back to Search
Start Over
Chinese registry of rheumatoid arthritis (CREDIT): I. Introduction and prevalence of remission in Chinese patients with rheumatoid arthritis.
- Source :
-
Clinical and experimental rheumatology [Clin Exp Rheumatol] 2018 Sep-Oct; Vol. 36 (5), pp. 836-840. Date of Electronic Publication: 2018 Mar 21. - Publication Year :
- 2018
-
Abstract
- Objectives: To introduce the Chinese Registry of rhEumatoiD arthrITis (CREDIT), which is the first nationwide, multicentre, online rheumatoid arthritis (RA) registry in China, and to depict major cross-sectional data and treatment strategies of Chinese RA patients.<br />Methods: RA patients who fulfilled the 2010 ACR/EULAR classification criteria for rheumatoid arthritis were recruited into the registry by their rheumatologists from 144 clinical centres in China. Data, including demographics, disease characteristics, co-morbidities, treatment, and adverse reactions, were collected and documented through the predefined protocol.<br />Results: 8071 registered patients (F:M = 4.03:1) were registered up to May 2017. Mean age at symptom onset and at diagnosis was 46.15±14.72y and 48.68±14.54y, respectively. Point prevalence of remission (95% CIs) was 14.88% (14.10-15.66%), 4.23% (3.79-4.66%), 4.25% (3.81-4.69%), and 4.27% (3.83-4.72%) according to DAS28-CRP, CDAI, SDAI, and the 2011 ACR/EULAR remission criteria, respectively. 38.84% and 38.11% of treatment-naïve patients (n=3262) were in moderate (3.2<DAS28-CRP≤5.1) and high (DAS28-CRP>5.1) disease activity, respectively. Among treatment-naïve patients, those who were initiated on treatment with bDMARDs had higher disease activity than those who were treated with csDMARDs (p<0.05). Three months after initiating bDMARDs, 19.29% (n=38) of patients achieved remission (DAS28-CRP<2.6).<br />Conclusions: The CREDIT registry is an effective tool for real-world study of RA patients in China. By providing information for diagnosis and treatment regimen, the CREDIT registry can enhance the application of treat-to-target (T2T) strategy and improve patient outcomes in China.
- Subjects :
- Adult
Aged
Arthritis, Rheumatoid diagnosis
Arthritis, Rheumatoid epidemiology
China epidemiology
Cross-Sectional Studies
Female
Humans
Male
Middle Aged
Practice Patterns, Physicians' trends
Prevalence
Remission Induction
Time Factors
Treatment Outcome
Antirheumatic Agents therapeutic use
Arthritis, Rheumatoid drug therapy
Registries
Subjects
Details
- Language :
- English
- ISSN :
- 0392-856X
- Volume :
- 36
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Clinical and experimental rheumatology
- Publication Type :
- Academic Journal
- Accession number :
- 29600939