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Studies on the anoxic inhibition of myocardial protein synthesis.

Authors :
Lesch M
Peterson MB
Source :
Recent advances in studies on cardiac structure and metabolism [Recent Adv Stud Cardiac Struct Metab] 1975; Vol. 8, pp. 101-15.
Publication Year :
1975

Abstract

The present study demonstrates that exposure of cardiac muscle to high levels of glucose during anoxia appears to retard damage to myocardial protein synthesis. The mechanism of this "glucose" effect is glucose-specific and appears related to the intracellular metabolism of glucose by the anoxic myocardium.

Subjects

Subjects :
Acidosis metabolism
Animals
Carbohydrate Metabolism
Chemical Fractionation
Depression, Chemical
Electrophoresis, Disc
Glucose metabolism
Hydrogen-Ion Concentration
Insulin pharmacology
Oxygen pharmacology
Phenylalanine metabolism
Phlorhizin pharmacology
Rabbits
Hypoxia metabolism
Muscle Proteins biosynthesis
Myocardium metabolism

Details

Language :
English
ISSN :
0363-5872
Volume :
8
Database :
MEDLINE
Journal :
Recent advances in studies on cardiac structure and metabolism
Publication Type :
Academic Journal
Accession number :
2956

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