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Colitis with wall thickening and edematous changes during oral administration of the powdered form of Qing-dai in patients with ulcerative colitis: a report of two cases.
- Source :
-
Clinical journal of gastroenterology [Clin J Gastroenterol] 2018 Aug; Vol. 11 (4), pp. 268-272. Date of Electronic Publication: 2018 Mar 16. - Publication Year :
- 2018
-
Abstract
- Orally administered Qing-dai, called indigo naturalis in Latin, is reportedly useful for the treatment of ulcerative colitis. We herein describe two patients with ulcerative colitis who developed colitis with wall thickening and edematous changes during oral administration of the powdered form of Qing-dai. In Case 1, a 35-year-old man developed colitis similar to ischemic colitis with bloody stool that recurred each time he ingested Qing-dai. He had no signs of recurrence upon withdrawal of Qing-dai. In Case 2, a 43-year-old woman underwent ileocecal resection for treatment of an intussusception 2 months after beginning oral administration of Qing-dai. Edema and congestion but no ulceration were present in the mucosa of the resected specimen. Both patients exhibited abdominal pain with bloody diarrhea, and abdominal computed tomography showed marked wall edema affecting an extensive portion of the large bowel.
- Subjects :
- Administration, Oral
Adult
Colitis diagnostic imaging
Colonoscopy
Edema chemically induced
Edema diagnostic imaging
Edema pathology
Female
Humans
Intestinal Mucosa diagnostic imaging
Intestinal Mucosa pathology
Male
Powders
Recurrence
Tomography, X-Ray Computed
Colitis chemically induced
Colitis pathology
Colitis, Ulcerative drug therapy
Drugs, Chinese Herbal administration & dosage
Drugs, Chinese Herbal adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 1865-7265
- Volume :
- 11
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Clinical journal of gastroenterology
- Publication Type :
- Academic Journal
- Accession number :
- 29549501
- Full Text :
- https://doi.org/10.1007/s12328-018-0851-7