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Synthesis of (2 H)-Indazoles through Rh(III)-Catalyzed Annulation Reaction of Azobenzenes with Sulfoxonium Ylides.

Authors :
Oh H
Han S
Pandey AK
Han SH
Mishra NK
Kim S
Chun R
Kim HS
Park J
Kim IS
Source :
The Journal of organic chemistry [J Org Chem] 2018 Apr 06; Vol. 83 (7), pp. 4070-4077. Date of Electronic Publication: 2018 Mar 20.
Publication Year :
2018

Abstract

The rhodium(III)-catalyzed C-H functionalization followed by intramolecular annulation reactions between azobenzenes and sulfoxonium ylides is described. This protocol leads to the efficient formation of 3-acyl (2 H)-indazoles with a range of substrate scope. A high level of chemoselectivity and functional group tolerance of this transformation were also observed.

Details

Language :
English
ISSN :
1520-6904
Volume :
83
Issue :
7
Database :
MEDLINE
Journal :
The Journal of organic chemistry
Publication Type :
Academic Journal
Accession number :
29547287
Full Text :
https://doi.org/10.1021/acs.joc.8b00501