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Improving maternal folate status to prevent infant neural tube defects: working group conclusions and a framework for action.
- Source :
-
Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2018 Feb; Vol. 1414 (1), pp. 5-19. - Publication Year :
- 2018
-
Abstract
- As infectious disease control programs achieve increasing success, further reductions in child mortality in low- and middle-income countries (LMICs) will require focused prevention strategies for birth defects and other noninfectious diseases. Neural tube defects (NTDs) can cause early death or lifelong disability. Preventing NTDs provides a feasible, significant opportunity to decrease the toll of birth defects and contribute to further reducing child mortality globally. The Micronutrient Forum convened a technical consultation on Folate Status in Women and Neural Tube Defects Prevention to develop a roadmap to inform and prioritize investments in NTD prevention in LMICs; help guide implementation efforts in terms of the feasibility of interventions and the potential for acceleration; and identify research and knowledge gaps. Here, we describe the impetus for and approach to the consultation and present the conclusions and a framework for developing a roadmap for action to accelerate NTD prevention in LMICs. The framework (1) provides options for action on folate status assessment; (2) outlines a way forward to develop and implement a time-bound global action plan for NTD prevention; and (3) identifies common impediments to NTD prevention, broad strategies to overcome or minimize these impediments, and basic building blocks necessary to accelerate action.<br /> (© 2018 The Authors. Annals of the New York Academy of Sciences published by Wiley Periodicals, Inc. on behalf of New York Academy of Sciences.)
- Subjects :
- Adolescent
Developing Countries
Epidemiological Monitoring
Erythrocytes metabolism
Female
Folic Acid administration & dosage
Folic Acid economics
Food, Fortified economics
Humans
Infant
Infant, Newborn
Male
Neural Tube Defects blood
Neural Tube Defects epidemiology
Pregnancy
Risk Factors
Vitamin B 12 administration & dosage
Folic Acid blood
Neural Tube Defects prevention & control
Subjects
Details
- Language :
- English
- ISSN :
- 1749-6632
- Volume :
- 1414
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Annals of the New York Academy of Sciences
- Publication Type :
- Report
- Accession number :
- 29532514
- Full Text :
- https://doi.org/10.1111/nyas.13593