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Lysosomal Acid Lipase Deficiency: Report of Five Cases across the Age Spectrum.

Authors :
Curiati MA
Kyosen SO
Pereira VG
PatrĂ­cio FRDS
Martins AM
Source :
Case reports in pediatrics [Case Rep Pediatr] 2018 Jan 21; Vol. 2018, pp. 4375434. Date of Electronic Publication: 2018 Jan 21 (Print Publication: 2018).
Publication Year :
2018

Abstract

Lysosomal acid lipase (LAL) deficiency is an autosomal recessive lysosomal storage disorder caused by mutations in the LIPA gene that leads to premature organ damage and mortality. We present retrospective data from medical records of 5 Brazilian patients, showing the broad clinical spectrum of the disease.

Details

Language :
English
ISSN :
2090-6803
Volume :
2018
Database :
MEDLINE
Journal :
Case reports in pediatrics
Publication Type :
Report
Accession number :
29527374
Full Text :
https://doi.org/10.1155/2018/4375434