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A CRISPR edit for heart disease.
- Source :
-
Nature [Nature] 2018 Mar 08; Vol. 555 (7695), pp. S23-S25. - Publication Year :
- 2018
- Subjects :
- Amino Acid Substitution
Angiopoietin-Like Protein 3
Angiopoietin-like Proteins deficiency
Angiopoietin-like Proteins genetics
Animals
Antibodies, Monoclonal pharmacology
Antibodies, Monoclonal therapeutic use
Antibodies, Monoclonal, Humanized
Apolipoprotein B-100 deficiency
Apolipoprotein B-100 genetics
Apolipoproteins C genetics
Cholesterol, LDL blood
Disease Models, Animal
Dystrophin genetics
Dystrophin metabolism
Heart Diseases blood
Heart Diseases therapy
Humans
Hypercholesterolemia blood
Hypercholesterolemia genetics
Hypercholesterolemia prevention & control
Lipoprotein(a) deficiency
Lipoprotein(a) genetics
Mice
Muscular Dystrophy, Duchenne genetics
Muscular Dystrophy, Duchenne therapy
Mutation
Myocardial Ischemia drug therapy
Myocardial Ischemia genetics
Myocardial Ischemia prevention & control
PCSK9 Inhibitors
Patient Safety
Proprotein Convertase 9 genetics
Proprotein Convertase 9 metabolism
Stroke drug therapy
Stroke genetics
Stroke prevention & control
CRISPR-Cas Systems genetics
Gene Editing methods
Gene Editing trends
Genetic Therapy methods
Genetic Therapy trends
Heart Diseases genetics
Heart Diseases prevention & control
Subjects
Details
- Language :
- English
- ISSN :
- 1476-4687
- Volume :
- 555
- Issue :
- 7695
- Database :
- MEDLINE
- Journal :
- Nature
- Publication Type :
- Academic Journal
- Accession number :
- 29517035
- Full Text :
- https://doi.org/10.1038/d41586-018-02482-4