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Genetics of biologically based psychological differences.

Authors :
Sallis H
Davey Smith G
Munafò MR
Source :
Philosophical transactions of the Royal Society of London. Series B, Biological sciences [Philos Trans R Soc Lond B Biol Sci] 2018 Apr 19; Vol. 373 (1744).
Publication Year :
2018

Abstract

In recent years, substantial effort has gone into disentangling the genetic contribution to individual differences in behaviour (such as personality and temperament traits). Heritability estimates from twin and family studies, and more recently using whole genome approaches, suggest a substantial genetic component to these traits. However, efforts to identify the genes that influence these traits have had relatively little success. Here, we review current work investigating the heritability of individual differences in behavioural traits and provide an overview of the results from genome-wide association analyses of these traits to date. In addition, we discuss the implications of these findings for the potential applications of Mendelian randomization.This article is part of the theme issue 'Diverse perspectives on diversity: multi-disciplinary approaches to taxonomies of individual differences'.<br /> (© 2018 The Authors.)

Details

Language :
English
ISSN :
1471-2970
Volume :
373
Issue :
1744
Database :
MEDLINE
Journal :
Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Publication Type :
Academic Journal
Accession number :
29483347
Full Text :
https://doi.org/10.1098/rstb.2017.0162