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Genetics of biologically based psychological differences.
- Source :
-
Philosophical transactions of the Royal Society of London. Series B, Biological sciences [Philos Trans R Soc Lond B Biol Sci] 2018 Apr 19; Vol. 373 (1744). - Publication Year :
- 2018
-
Abstract
- In recent years, substantial effort has gone into disentangling the genetic contribution to individual differences in behaviour (such as personality and temperament traits). Heritability estimates from twin and family studies, and more recently using whole genome approaches, suggest a substantial genetic component to these traits. However, efforts to identify the genes that influence these traits have had relatively little success. Here, we review current work investigating the heritability of individual differences in behavioural traits and provide an overview of the results from genome-wide association analyses of these traits to date. In addition, we discuss the implications of these findings for the potential applications of Mendelian randomization.This article is part of the theme issue 'Diverse perspectives on diversity: multi-disciplinary approaches to taxonomies of individual differences'.<br /> (© 2018 The Authors.)
- Subjects :
- Genetics, Population
Genome, Human
Genome-Wide Association Study
Genotype
Humans
Individuality
Mendelian Randomization Analysis
Personality Disorders diagnosis
Personality Disorders physiopathology
Personality Disorders psychology
Phenotype
Polymorphism, Single Nucleotide
Genetic Heterogeneity
Inheritance Patterns
Neuroticism
Personality Disorders genetics
Quantitative Trait, Heritable
Subjects
Details
- Language :
- English
- ISSN :
- 1471-2970
- Volume :
- 373
- Issue :
- 1744
- Database :
- MEDLINE
- Journal :
- Philosophical transactions of the Royal Society of London. Series B, Biological sciences
- Publication Type :
- Academic Journal
- Accession number :
- 29483347
- Full Text :
- https://doi.org/10.1098/rstb.2017.0162