Back to Search
Start Over
Comparison of the Temperature Influence on the Activity of Currently Available Procalcitonin Reagents.
- Source :
-
Clinical laboratory [Clin Lab] 2018 Jan 01; Vol. 64 (1), pp. 201-204. - Publication Year :
- 2018
-
Abstract
- Background: Procalcitonin (PCT) is a stable biomarker for bacterial infections; however, limited data is available on new trivalent reagents. We evaluated temperature influence on the activity of PCT reagents.<br />Methods: Using both conventional and trivalent reagents, we measured PCT levels of 30 clinical samples, stored residuum at refrigerator (4°C) and room temperature (24°C), and reexamined it after 24 hours. We defined a reduction rate as a percentage of PCT level at 24 hours compared to that after defrost and evaluated a ratio of reduction rate in 4°C to that in 24°C.<br />Results: The reduction rate at room temperature decreased significantly compared to that in the refrigerated condition for all the reagents examined (p < 0.001). In addition, the ratio of reduction rate between the conventional and trivalent reagents showed a significant difference (p < 0.001).<br />Conclusions: The serum PCT levels significantly decrease at room temperature, particularly when using newer trivalent reagents.
Details
- Language :
- English
- ISSN :
- 1433-6510
- Volume :
- 64
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Clinical laboratory
- Publication Type :
- Academic Journal
- Accession number :
- 29479870
- Full Text :
- https://doi.org/10.7754/Clin.Lab.2017.170510