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Cost-Effectiveness of a Specialized Oral Nutritional Supplementation for Malnourished Older Adult Patients in Spain.
- Source :
-
Nutrients [Nutrients] 2018 Feb 22; Vol. 10 (2). Date of Electronic Publication: 2018 Feb 22. - Publication Year :
- 2018
-
Abstract
- Malnutrition has been related to prolonged hospital stays, and to increases in readmission and mortality rates. In the NOURISH (Nutrition effect On Unplanned Readmissions and Survival in Hospitalized patients) study, administering a high protein oral nutritional supplement (ONS) containing beta-hydroxy-beta-methylbutyrate (HP-HMB) to hospitalised older adult patients led to a significant improvement in survival compared with a placebo treatment. The aim of this study was to determine whether HP-HMB would be cost-effective in Spain. We performed a cost-effectiveness analysis from the perspective of the Spanish National Health System using time horizons of 90 days, 180 days, 1 year, 2 years, 5 years and lifetime. The difference in cost between patients treated with HP-HMB and placebo was €332.75. With the 90 days time horizon, the difference in life years gained (LYG) between both groups was 0.0096, resulting in an incremental cost-effectiveness ratio (ICER) of €34,700.62/LYG. With time horizons of 180 days, 1 year, 2 years, 5 years and lifetime, the respective ICERs were €13,711.68, €3377.96, €2253.32, €1127.34 and €563.84/LYG. This analysis suggests that administering HP-HMB to older adult patients admitted to Spanish hospitals during hospitalisation and after discharge could be a cost-effective intervention that would improve survival with a reduced marginal cost.<br />Competing Interests: R.S.B. and S.G. are employees at Abbott Laboratories Ltd. D.M.L. is an employee at Oblikue Consulting, which provided paid consulting services to Abbott Laboratories Ltd. for the development of this study.
- Subjects :
- Administration, Oral
Age Factors
Aged
Cost Savings
Cost-Benefit Analysis
Dietary Proteins adverse effects
Enteral Nutrition adverse effects
Female
Geriatric Assessment
Hospitalization economics
Humans
Male
Malnutrition diagnosis
Malnutrition physiopathology
Models, Economic
Spain
Time Factors
Treatment Outcome
Valerates adverse effects
Dietary Proteins administration & dosage
Dietary Proteins economics
Enteral Nutrition economics
Hospital Costs
Malnutrition economics
Malnutrition therapy
Nutritional Status
Valerates administration & dosage
Valerates economics
Subjects
Details
- Language :
- English
- ISSN :
- 2072-6643
- Volume :
- 10
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Nutrients
- Publication Type :
- Academic Journal
- Accession number :
- 29470402
- Full Text :
- https://doi.org/10.3390/nu10020246