Back to Search
Start Over
American Heart Association's Life's Simple 7 at Middle Age and Prognosis After Myocardial Infarction in Later Life.
- Source :
-
Journal of the American Heart Association [J Am Heart Assoc] 2018 Feb 17; Vol. 7 (4). Date of Electronic Publication: 2018 Feb 17. - Publication Year :
- 2018
-
Abstract
- Background: The American Heart Association recommends focusing on 7 health factors (Life's Simple 7) for primordial prevention of cardiovascular health. However, whether greater adherence to Life's Simple 7 in midlife improves prognosis after myocardial infarction (MI) in later life is unknown.<br />Methods and Results: In 1277 participants who developed MI during the ARIC (Atherosclerosis Risk in Communities) Study follow-up, a 14-point score of Life's Simple 7 was constructed according to the status (2 points for ideal, 1 point for intermediate, and 0 points for poor) of each of 7 factors (smoking, adiposity, physical activity, diet, total cholesterol, blood pressure, and fasting glucose) at baseline (1987-1989). Hazard ratios for composite and individual adverse outcomes of all-cause mortality, cardiovascular mortality, recurrent MI, heart failure, and stroke were calculated according to Life's Simple 7 score. During a median follow-up of 3.3 years, 918 participants (72%) had subsequent adverse outcomes after MI. Life's Simple 7 score at middle age was inversely associated with adverse outcomes after MI (adjusted hazard ratios of composite outcome, 0.57 [95% confidence interval, 0.39-0.84] if score is ≥10, 0.78 [95% confidence interval, 0.57-1.07] if score is 7-9, and 0.82 [95% confidence interval, 0.60-1.11] if score is 4-6 versus ≤3). The association was largely independent of access to care and MI severity. Individual factors related to better prognosis after MI were ideal nonsmoking, body mass index, blood pressure, and fasting glucose.<br />Conclusions: Optimal Life's Simple 7 at middle age was associated with better prognosis after MI in later life. Our findings suggest a secondary prevention benefit of having better cardiovascular health status in midlife.<br /> (© 2018 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.)
- Subjects :
- Adiposity
Age Factors
American Heart Association
Biomarkers blood
Blood Pressure
Body Mass Index
Cholesterol blood
Diet, Healthy
Exercise
Glucose analysis
Health Status
Humans
Incidence
Male
Middle Aged
Myocardial Infarction diagnosis
Myocardial Infarction epidemiology
Myocardial Infarction physiopathology
Prognosis
Prospective Studies
Protective Factors
Risk Assessment
Risk Factors
Smoking adverse effects
Smoking Cessation
Time Factors
United States epidemiology
Healthy Lifestyle
Myocardial Infarction prevention & control
Risk Reduction Behavior
Secondary Prevention methods
Subjects
Details
- Language :
- English
- ISSN :
- 2047-9980
- Volume :
- 7
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Journal of the American Heart Association
- Publication Type :
- Academic Journal
- Accession number :
- 29455158
- Full Text :
- https://doi.org/10.1161/JAHA.117.007658