Cancer gene-panel testing identifies two loss-of-function alleles in PALB2 and PTEN.

Authors :: Avgerinou C
Fostira F
Economopoulou P
Psyrri A
Source :: Clinical genetics [Clin Genet] 2018 Jun; Vol. 93 (6), pp. 1250-1251. Date of Electronic Publication: 2018 Feb 11.
Publication Year :: 2018
Abstract: Synchronous loss-of-function mutations in the cancer predisposing genes, PTEN and PALB2 identified by multigene panel.<br /> (© 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)

Subjects :: Adult
Female
Genetic Predisposition to Disease
Hamartoma Syndrome, Multiple genetics
Humans
Male
Pedigree
Fanconi Anemia Complementation Group N Protein genetics
Genetic Testing methods
Loss of Function Mutation genetics
Neoplasms genetics
PTEN Phosphohydrolase genetics

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