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[Newborn of mother with HELLP syndrome: characteristics and role of prematurity, low birth-weight and leukopenia in evolution].
- Source :
-
Boletin medico del Hospital Infantil de Mexico [Bol Med Hosp Infant Mex] 2015 Sep - Oct; Vol. 72 (5), pp. 318-324. Date of Electronic Publication: 2015 Oct 19. - Publication Year :
- 2015
-
Abstract
- Background: HELLP syndrome is a serious hypertensive disorder of pregnancy with important neonatal problems in the newborn. The objective of this work was to determine the characteristics of these infants and its neonatal evolution.<br />Methods: A retrospective observational study of all newborns of mothers with HELLP syndrome born in a university hospital between January 1, 2008 and December 31, 2013 was carried out. Thirty-three infants from 28 pregnancies (five twin gestations) were studied. A descriptive and comparative analysis between groups and a multivariate analysis of factors associated with mortality in the series took place.<br />Results: Of 33 newborns studied (2.2 newborns/1,000 infants total), two were stillbirths (6.1% of the total) and four died after birth (12.9% of live neonates) with overall perinatal mortality of 18.2%. Pregnancies in 28 infants ended before 37 weeks (84.8%) and 11 pregnancies ended before week 32 (33.3%). Seven infants weighed<1500g (four weighed <1000g). Of the 31 live births, 13 infants were in a <10th percentile weight for gestational age (41.9%), 20 needed neonatal resuscitation (64.5%) and 14 had leukopenia at birth (45.2%). In the final logistic regression, neonatal mortality was associated with extreme prematurity regardless of underweight, leukopenia and/or need for neonatal resuscitation.<br />Conclusions: Children of mothers with HELLP syndrome have a high mortality associated with extreme prematurity, independent of the presence of leukopenia, low weight for gestational age and need for neonatal resuscitation.<br /> (Copyright © 2015 Hospital Infantil de México Federico Gómez. Publicado por Masson Doyma México S.A. All rights reserved.)
Details
- Language :
- Spanish; Castilian
- ISSN :
- 1665-1146
- Volume :
- 72
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Boletin medico del Hospital Infantil de Mexico
- Publication Type :
- Academic Journal
- Accession number :
- 29421530
- Full Text :
- https://doi.org/10.1016/j.bmhimx.2015.09.006