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Onco-testicular sperm extraction (Onco-TESE) from a single testis with metachronous bilateral testicular cancer: a case report.
- Source :
-
Basic and clinical andrology [Basic Clin Androl] 2018 Jan 25; Vol. 28, pp. 1. Date of Electronic Publication: 2018 Jan 25 (Print Publication: 2018). - Publication Year :
- 2018
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Abstract
- Background: Although oncologic testicular sperm extraction (onco-TESE) has been increasingly practiced, the evidence of onco-TESE performed in patients with testicular cancer is insufficient. Furthermore, in bilateral testicular cancer, accounting for 0.5%-1% of testicular cancers, onco-TESE is more challenging and has been insufficiently reported.<br />Case Presentation: Here we report the case of a 25-year-old man who underwent onco-TESE from his residual single testis with a nonseminomatous germ cell tumor that occurred 5 years after orchiectomy of the contralateral testis. A second orchiectomy and simultaneous TESE from the noncancerous testicular tissue were performed. The pathological diagnosis was germ cell tumors, tumors of more than one histological type (embryonal carcinoma, immature teratoma, yolk sac tumor, seminoma, and choriocarcinoma; pT1N0M0). The patient subsequently married and hoped for fatherhood 3 years later. Whereas histological diagnosis of the normal testicular tissue was Johnsen score 6 (maturation arrest), morphologically normal and motile sperms were successfully retrieved from thawed TESE samples and used for multiple cycles of intracytoplasmic sperm injection. Although the conception has not been succeeded to date, ICSI attempts have been continuing.<br />Conclusion: This case demonstrates the effectiveness of onco-TESE for challenging cases such as bilateral and nonseminmatous testicular cancer.<br />Competing Interests: Not applicableWritten informed consent for publication of clinical details and clinical images of this case report was obtained from the patient.The authors declare that they have no competing interests.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Details
- Language :
- English
- ISSN :
- 2051-4190
- Volume :
- 28
- Database :
- MEDLINE
- Journal :
- Basic and clinical andrology
- Publication Type :
- Report
- Accession number :
- 29416867
- Full Text :
- https://doi.org/10.1186/s12610-018-0066-2