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Spontaneous 15 N Nuclear Spin Hyperpolarization in Metal-Free Activation of Parahydrogen by Molecular Tweezers.

Authors :
Sorochkina K
Zhivonitko VV
Chernichenko K
Telkki VV
Repo T
Koptyug IV
Source :
The journal of physical chemistry letters [J Phys Chem Lett] 2018 Feb 15; Vol. 9 (4), pp. 903-907. Date of Electronic Publication: 2018 Feb 08.
Publication Year :
2018

Abstract

The ability of frustrated Lewis pairs (FLPs) to activate H <subscript>2</subscript> is of significant interest for metal-free catalysis. The activation of H <subscript>2</subscript> is also the key element of parahydrogen-induced polarization (PHIP), one of the nuclear spin hyperpolarization techniques. It is demonstrated that o-phenylene-based ansa-aminoboranes (AABs) can produce <superscript>1</superscript> H nuclear spin hyperpolarization through a reversible interaction with parahydrogen at ambient temperatures. Heteronuclei are useful in NMR and MRI as well because they have a broad chemical shift range and long relaxation times and may act as background-free labels. We report spontaneous formation of <superscript>15</superscript> N hyperpolarization of the N-H site for a family of AABs. The process is efficient at the high magnetic field of an NMR magnet (7 T), and it provides up to 350-fold <superscript>15</superscript> N signal enhancements. Different hyperpolarization effects are observed with various AAB structures and in a broad temperature range. Spontaneous hyperpolarization, albeit an order of magnitude weaker than that for <superscript>15</superscript> N, was also observed for <superscript>11</superscript> B nuclei.

Details

Language :
English
ISSN :
1948-7185
Volume :
9
Issue :
4
Database :
MEDLINE
Journal :
The journal of physical chemistry letters
Publication Type :
Academic Journal
Accession number :
29401399
Full Text :
https://doi.org/10.1021/acs.jpclett.7b03433