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[Impact of routine brain imaging in the initial management of lung cancer].

Authors :
Niviere P
Sculier JP
Meert AP
Berghmans T
Source :
Revue des maladies respiratoires [Rev Mal Respir] 2018 Jan; Vol. 35 (1), pp. 55-61. Date of Electronic Publication: 2018 Feb 04.
Publication Year :
2018

Abstract

Introduction: Brain metastases are a common complication of bronchial carcinoma (BC). There is no consensus as to the need to undertake a systematic search for these lesions during the initial assessment. The aim of this study was to evaluate the contribution of brain imaging in the initial evaluation of patients with CB.<br />Methods: We undertook a retrospective analysis of patients treated in the Thoracic Oncology Clinic at the Institute Jules-Bordet between 01/09/2008 and 31/08/2013, who were treatment-naïve and were having a full diagnostic work-up including brain imaging.<br />Results: Four hundred and sixty-three patients consecutively diagnosed with BC were included. Brain magnetic resonance imaging and/or CT-scan showed brain metastases in 101 patients (21.8%), of whom 67 had no symptoms suggestive of brain metastatic disease. The addition of a brain imaging into the work-up procedure resulted in a stage migration for 30 patients (6.5%), mainly otherwise staged IIIA (n=10) or IIIB (n=14) without brain imaging.<br />Conclusion: The addition of brain imaging in the initial assessment of bronchial carcinoma allows the identification of brain metastases in one case among 5, of which 2/3 are asymptomatic. This leads to a change in staging, primarily for disease otherwise considered to be stage III.<br /> (Copyright © 2017 SPLF. Published by Elsevier Masson SAS. All rights reserved.)

Details

Language :
French
ISSN :
1776-2588
Volume :
35
Issue :
1
Database :
MEDLINE
Journal :
Revue des maladies respiratoires
Publication Type :
Academic Journal
Accession number :
29397303
Full Text :
https://doi.org/10.1016/j.rmr.2017.11.004