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A naturally occurring epiallele associates with leaf senescence and local climate adaptation in Arabidopsis accessions.
- Source :
-
Nature communications [Nat Commun] 2018 Jan 31; Vol. 9 (1), pp. 460. Date of Electronic Publication: 2018 Jan 31. - Publication Year :
- 2018
-
Abstract
- Epigenetic variation has been proposed to facilitate adaptation to changing environments, but evidence that natural epialleles contribute to adaptive evolution has been lacking. Here we identify a retrotransposon, named "NMR19" (naturally occurring DNA methylation variation region 19), whose methylation and genomic location vary among Arabidopsis thaliana accessions. We classify NMR19 as NMR19-4 and NMR19-16 based on its location, and uncover NMR19-4 as an epiallele that controls leaf senescence by regulating the expression of PHEOPHYTIN PHEOPHORBIDE HYDROLASE (PPH). We find that the DNA methylation status of NMR19-4 is stably inherited and independent of genetic variation. In addition, further analysis indicates that DNA methylation of NMR19-4 correlates with local climates, implying that NMR19-4 is an environmentally associated epiallele. In summary, we discover a novel epiallele, and provide mechanistic insights into its origin and potential function in local climate adaptation.
- Subjects :
- Adaptation, Physiological genetics
Alleles
Arabidopsis genetics
Arabidopsis Proteins genetics
Arabidopsis Proteins metabolism
DNA Methylation
DNA-Binding Proteins genetics
DNA-Binding Proteins metabolism
Epigenesis, Genetic
Evolution, Molecular
Gene Expression Regulation, Plant
Genetic Variation
Hydrolases genetics
Hydrolases metabolism
Long Interspersed Nucleotide Elements
Mutation
Plant Leaves genetics
Transcription Factors genetics
Transcription Factors metabolism
Acclimatization genetics
Arabidopsis physiology
Plant Leaves physiology
Retroelements genetics
Subjects
Details
- Language :
- English
- ISSN :
- 2041-1723
- Volume :
- 9
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Nature communications
- Publication Type :
- Academic Journal
- Accession number :
- 29386641
- Full Text :
- https://doi.org/10.1038/s41467-018-02839-3