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Ruthenium-Catalyzed Hydrogenation of Carbocyclic Aromatic Amines: Access to Chiral Exocyclic Amines.
- Source :
-
Organic letters [Org Lett] 2018 Feb 16; Vol. 20 (4), pp. 1094-1097. Date of Electronic Publication: 2018 Jan 30. - Publication Year :
- 2018
-
Abstract
- The first highly enantioselective hydrogenation of carbocyclic aromatic amines has been successfully realized using in situ-generated chiral ruthenium complex as catalyst, affording facile access to chiral exocyclic amines with up to 98% ee.
Details
- Language :
- English
- ISSN :
- 1523-7052
- Volume :
- 20
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Organic letters
- Publication Type :
- Academic Journal
- Accession number :
- 29380604
- Full Text :
- https://doi.org/10.1021/acs.orglett.7b04060