Arrangement of coding and intervening sequences of chicken lysozyme gene.

Authors :: Lindenmaier W
Nguyen-Huu MC
Lurz R
Stratmann M
Blin N
Wurtz T
Hauser HJ
Sippel AE
Schütz G
Source :: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1979 Dec; Vol. 76 (12), pp. 6196-200.
Publication Year :: 1979
Abstract: Hybrid phages that contain chicken lysozyme gene sequences have been isolated from a chicken DNA library. Two overlapping clones covering a region of 22 kilobase pairs around this gene have been studied by restriction mapping. Southern hybridization, and electron microscopic analysis of hybrids between lysozyme mRNA and the cloned cellular DNA. Three intervening sequences interrupt the lysozyme structural gene. The cellular gene is at least 3.9 kilobases long, about 6 times the length of the structural gene.

Subjects :: Animals
Base Sequence
DNA Restriction Enzymes
DNA, Recombinant
Nucleic Acid Conformation
Nucleic Acid Hybridization
Nucleic Acid Precursors genetics
RNA, Messenger genetics
Genes
Muramidase genetics

Language :: English
ISSN :: 0027-8424
Volume :: 76
Issue :: 12
Database :: MEDLINE
Journal :: Proceedings of the National Academy of Sciences of the United States of America
Publication Type :: Academic Journal
Accession number :: 293713
Full Text :: https://doi.org/10.1073/pnas.76.12.6196