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Volumetric Modulated Arc (Radio) Therapy in Pets Treatment: The "La Cittadina Fondazione" Experience.

Authors :
Dolera M
Malfassi L
Carrara N
Finesso S
Marcarini S
Mazza G
Pavesi S
Sala M
Urso G
Source :
Cancers [Cancers (Basel)] 2018 Jan 24; Vol. 10 (2). Date of Electronic Publication: 2018 Jan 24.
Publication Year :
2018

Abstract

Volumetric Modulated Arc Therapy (VMAT) is a modern technique, widely used in human radiotherapy, which allows a high dose to be delivered to tumor volumes and low doses to the surrounding organs at risk (OAR). Veterinary clinics takes advantage of this feature due to the small target volumes and distances between the target and the OAR. Sparing the OAR permits dose escalation, and hypofractionation regimens reduce the number of treatment sessions with a simpler manageability in the veterinary field. Multimodal volumes definition is mandatory for the small volumes involved and a positioning device precisely reproducible with a setup confirmation is needed before each session for avoiding missing the target. Additionally, the elaborate treatment plan must pursue hard constraints and objectives, and its feasibility must be evaluated with a per patient quality control. The aim of this work is to report results with regard to brain meningiomas and gliomas, trigeminal nerve tumors, brachial plexus tumors, adrenal tumors with vascular invasion and rabbit thymomas, in comparison with literature to determine if VMAT is a safe and viable alternative to surgery or chemotherapy alone, or as an adjuvant therapy in pets.<br />Competing Interests: The authors declare no conflict of interest

Details

Language :
English
ISSN :
2072-6694
Volume :
10
Issue :
2
Database :
MEDLINE
Journal :
Cancers
Publication Type :
Academic Journal
Accession number :
29364837
Full Text :
https://doi.org/10.3390/cancers10020030