Back to Search
Start Over
Anti-MuSK Antibody-positive Myasthenia Gravis Successfully Treated with Outpatient Periodic Weekly Blood Purification Therapy.
- Source :
-
Internal medicine (Tokyo, Japan) [Intern Med] 2018 May 15; Vol. 57 (10), pp. 1455-1458. Date of Electronic Publication: 2018 Jan 11. - Publication Year :
- 2018
-
Abstract
- A 37-year-old man with anti-muscle-specific tyrosine kinase (MuSK) antibody-positive myasthenia gravis (MG) presented with subacute progressive dysphagia and muscle weakness of the neck and bilateral upper extremities. Conventional immune-suppressive treatments and high-dose intravenous immunoglobulin were ineffective. He then displayed repeated exacerbations and remissions over the course of two years, despite two to four sessions of plasma exchange (PE) every two months. The patient was successfully treated with outpatient periodic weekly blood purification therapy with alternative PE and double-filtration plasmapheresis using an internal shunt. This case report suggests the benefits of blood purification therapy with an internal shunt against anti-MuSK antibody-positive MG.
- Subjects :
- Adult
Deglutition Disorders etiology
Humans
Immunoglobulins, Intravenous therapeutic use
Male
Muscle Weakness etiology
Myasthenia Gravis diagnosis
Tyrosine therapeutic use
Ambulatory Care
Autoantibodies blood
Myasthenia Gravis immunology
Myasthenia Gravis therapy
Plasma Exchange
Plasmapheresis
Receptor Protein-Tyrosine Kinases immunology
Receptors, Cholinergic immunology
Subjects
Details
- Language :
- English
- ISSN :
- 1349-7235
- Volume :
- 57
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Internal medicine (Tokyo, Japan)
- Publication Type :
- Academic Journal
- Accession number :
- 29321424
- Full Text :
- https://doi.org/10.2169/internalmedicine.9466-17