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What's in a Name? Cell Fate Reprogramming in Sarcomagenesis.

Authors :
Jones KB
Source :
Cancer cell [Cancer Cell] 2018 Jan 08; Vol. 33 (1), pp. 5-7.
Publication Year :
2018

Abstract

Differentiation features in cancer cells are typically attributed to the cell of origin. In this issue of Cancer Cell, Drummond et al. demonstrate a transdifferentiation program apparent in rhabdomyosarcomas (cancers with skeletal muscle differentiation features) arising through cell fate reprogramming from a single oncogene activation in endothelial cell precursors.<br /> (Copyright © 2017 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1878-3686
Volume :
33
Issue :
1
Database :
MEDLINE
Journal :
Cancer cell
Publication Type :
Academic Journal
Accession number :
29316432
Full Text :
https://doi.org/10.1016/j.ccell.2017.12.005