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Localization of amylin-like immunoreactivity in the striped velvet gecko pancreas.
- Source :
-
Anatomia, histologia, embryologia [Anat Histol Embryol] 2018 Apr; Vol. 47 (2), pp. 159-166. Date of Electronic Publication: 2018 Jan 08. - Publication Year :
- 2018
-
Abstract
- Immunohistochemical techniques were employed to investigate the distribution of amylin-like immunoreactive cells in the pancreas of gecko Homopholis fasciata. Four types of endocrine cells were distinguished: insulin immunoreactive (B cells), pancreatic polypeptide immunoreactive (PP cells), glucagon and pancreatic polypeptide immunoreactive (A/PP cells) and somatostatin immunoreactive cells (D cells). Pancreatic islets contained B, A/PP and D cells, whereas extrainsular regions contained B, D and PP cells. In the pancreatic islets, amylin-like immunoreactive cells corresponded to B cells, but not to A/PP or D cells. In the extrainsular regions, amylin-like immunoreactive cells corresponded to either B or PP cells. Amylin secreted from intrainsular B cells may regulate pancreatic hormone secretion in an autocrine and/or a paracrine fashion. On the other hand, amylin secreted from extrainsular PP and B cells, and/or intrainsular B cells may participate in the modulation of calcium homoeostasis in an endocrine fashion.<br /> (© 2018 Blackwell Verlag GmbH.)
- Subjects :
- Animals
Endocrine Cells metabolism
Glucagon immunology
Glucagon metabolism
Insulin immunology
Insulin metabolism
Insulin Secretion
Islet Amyloid Polypeptide immunology
Lizards
Somatostatin immunology
Somatostatin metabolism
B-Lymphocytes cytology
Endocrine Cells classification
Glucagon-Secreting Cells cytology
Immunohistochemistry veterinary
Islet Amyloid Polypeptide metabolism
Pancreatic Polypeptide-Secreting Cells cytology
Subjects
Details
- Language :
- English
- ISSN :
- 1439-0264
- Volume :
- 47
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Anatomia, histologia, embryologia
- Publication Type :
- Academic Journal
- Accession number :
- 29315753
- Full Text :
- https://doi.org/10.1111/ahe.12337