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A retrospective cohort study of patients treated with anti-tuberculous therapy for presumed ocular tuberculosis.
- Source :
-
Journal of ophthalmic inflammation and infection [J Ophthalmic Inflamm Infect] 2017 Dec 04; Vol. 7 (1), pp. 23. Date of Electronic Publication: 2017 Dec 04. - Publication Year :
- 2017
-
Abstract
- Background: Uveitis involving the posterior segment is a significant and potentially blinding condition. The diagnosis and treatment of patients with uveitis associated with tuberculosis remains controversial, and commonly, patients are systemically well. Use of the interferon-gamma release assays has added to the controversy, as the significance of a positive test may be uncertain. We aim to report the outcomes of anti-tuberculous treatment in a cohort of patients treated in Birmingham, for presumed "ocular tuberculosis", based on clinical findings, systemic assessment and specific testing for tuberculosis.<br />Results: We found that in our cohort of 41 patients treated between 2010 and 2014, the majority achieved disease-free remission, even in cases where anti-tuberculous treatment was delayed.<br />Conclusions: Despite controversy, this study strongly supports the use of anti-tuberculous therapy in such patients and highlights the need for formal prospective trials and treatment protocols.
Details
- Language :
- English
- ISSN :
- 1869-5760
- Volume :
- 7
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Journal of ophthalmic inflammation and infection
- Publication Type :
- Academic Journal
- Accession number :
- 29204932
- Full Text :
- https://doi.org/10.1186/s12348-017-0141-4