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Tuberculosis among migrants in Bishkek, the capital of the Kyrgyz Republic.

Authors :
Goncharova O
Denisiuk O
Zachariah R
Davtyan K
Nabirova D
Acosta C
Kadyrov A
Source :
Public health action [Public Health Action] 2017 Sep 21; Vol. 7 (3), pp. 218-223.
Publication Year :
2017

Abstract

Setting: Twenty-two first-line, two second-line and one tertiary health facility in Bishkek, the capital of Kyrgyzstan. Objectives: Among migrants, a marginalised population at risk for acquiring and transmitting tuberculosis (TB), we determined the proportion with TB among all registered TB cases. For those registered at primary-level facilities, we then reported on their demographic and clinical profiles and TB treatment outcomes. Design: This was a retrospective cohort analysis of 2012-2013 programme data. Results: Of 2153 TB patients registered in all health facilities, 969 (45%) were migrants, of whom 454 were registered in first-line facilities. Of these, 27% were cross-border migrants, 50% had infectious TB and 12% had drug-resistant TB. Treatment success was 74% for new cases and 44% for retreatment TB (the World Health Organization target is ⩾85%). Failure in new and retreatment TB patients was respectively 8% and 25%. Twenty-six individuals started on a first-line anti-tuberculosis regimen failed due to multidrug-resistant TB. Eight (25%) of 32 individuals on a retreatment TB regimen also failed. Loss to follow-up was 10% for new and 19% for retreatment TB. Conclusion: Migrants constituted almost half of all TB patients, drug resistance is prevalent and treatment outcomes unsatisfactory. Fostering inter-country collaboration and prioritising rapid TB diagnostics (Xpert <superscript>®</superscript> MTB/RIF) and innovative ways forward for improving treatment outcomes is urgent.<br />Competing Interests: Conflicts of interest: none declared.

Details

Language :
English
ISSN :
2220-8372
Volume :
7
Issue :
3
Database :
MEDLINE
Journal :
Public health action
Publication Type :
Academic Journal
Accession number :
29201657
Full Text :
https://doi.org/10.5588/pha.17.0002