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Use of autologous bone marrow cells concentrate enriched with platelet-fibrin on extensor mechanism allograft reconstruction for extensor mechanism failure following total knee arthroplasty.

Authors :
Giannotti S
Parchi PD
Colasanti GB
Agostini G
Moreschini F
Cataldi C
Ferrata P
Capanna R
Source :
Journal of biological regulators and homeostatic agents [J Biol Regul Homeost Agents] 2017 Oct-Dec; Vol. 31 (4 suppl 1), pp. 107-111.
Publication Year :
2017

Abstract

Allografts techniques remain the best reconstructive strategy for chronic extensor mechanism lesions after total knee arthroplasty (3) but outcomes depend strictly on the host tissue-allograft junctions healing. The purpose of this study is to evaluate if modern techniques of adding autologous bone marrow cells concentrate enriched with platelet-rich fibrin, provide better healing of the allograft. We present the case of an 86 years old patient affected by patellar tendon rupture after TKA. A whole extensor mechanism allograft was performed adding a bone marrow cells concentrate enriched with platelet-rich fibrin on the host tissue-allograft junctions. Preoperatively and at each follow-up the value of Knee Society Score and radiographic consolidation signs were recorded. Radiographic controls showed clear signs of consolidation already at 1 months follow-up and a solid fusion at 3 months. This case report describes a valid method to improve healing using a tissue-construct engineered with stem cells and growth factors.

Details

Language :
English
ISSN :
0393-974X
Volume :
31
Issue :
4 suppl 1
Database :
MEDLINE
Journal :
Journal of biological regulators and homeostatic agents
Publication Type :
Academic Journal
Accession number :
29186946