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[Regulation of bone remodeling by anti-resorptives.]

Authors :
Inoue D
Source :
Clinical calcium [Clin Calcium] 2017; Vol. 27 (12), pp. 1775-1783.
Publication Year :
2017

Abstract

Classical anti-resorptives such as bisphosphonates inhibit remodeling, leading to decreases in both bone resorption and formation markers. Changes in these markers are useful in predicting future bone mineral density and fracture risk to some extent. More recently developed drugs such as denosumab and odanacatib, which also fall into the category of anti-resorptives, show unique effects on modeling and remodeling. This overview summarizes action of anti-resorptives from a viewpoint of remodeling.

Details

Language :
Japanese
ISSN :
0917-5857
Volume :
27
Issue :
12
Database :
MEDLINE
Journal :
Clinical calcium
Publication Type :
Academic Journal
Accession number :
29179173
Full Text :
https://doi.org/CliCa171217751783