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Morphological Evaluation of the Influence of the Peptide Complex from Tissue of Porcine Kidneys on the Experimental Urolithiasis.

Authors :
Zharikov AY
Kiselev VI
Saldan IP
Zharikova GV
Lepilov AV
Bobrov IP
Source :
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2017 Dec; Vol. 164 (2), pp. 207-210. Date of Electronic Publication: 2017 Nov 27.
Publication Year :
2017

Abstract

We performed morphological analysis of the effect of the peptide complex from porcine kidneys on the course of experimental urolithiasis modeled in rats by treatment with 1% ethylene glycol solution (in drinking water) for 6 weeks. The peptide complex obtained by acetic acid extraction was administered in a dose of 15 mg. Administration of the peptide complex to animals with experimental kidney stone disease leads to 100% destruction of large and medium stones to the "dust" granularity.

Details

Language :
English
ISSN :
1573-8221
Volume :
164
Issue :
2
Database :
MEDLINE
Journal :
Bulletin of experimental biology and medicine
Publication Type :
Academic Journal
Accession number :
29177872
Full Text :
https://doi.org/10.1007/s10517-017-3959-8