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Report: Prevalence and antibiotic trials against Salmonella enterica isolated from diarrheic lambs and kids.

Authors :
Iqbal MK
Ijaz M
Aslam HB
Farooqi SH
Ahmad SS
Akhtar R
Source :
Pakistan journal of pharmaceutical sciences [Pak J Pharm Sci] 2017 Nov; Vol. 30 (6), pp. 2265-2269.
Publication Year :
2017

Abstract

Salmonella enterica (S. enterica) is the major zoonotic threat for small ruminants and humans responsible for huge economic losses and high mortality in Pakistan. Lambs and kids of Lahore district were examined to determine the prevalence, hematology and chemotherapy of S. enterica. A total of 200 diarrheic samples (n=100 lambs; n=100 kids) were collected and examined; 59 (29.50%) were found positive for S. enterica. Lambs had lightly greater prevalence (31%) than kids (29%). The frequency analysis (OR=1.16 [reciprocal =0.87]) showed non-significant difference in both the lambs and kids. The significant decrease (Pℜ0.001) in hemoglobin, pack cell volume and total erythrocyte count was observed in infected lambs and kids. Results of in-vitro antibiotic susceptibility test revealed that S. enteric isolated from both lambs and kids were susceptible to levofloxacin, ciprofloxacin, ofloxacin, gentamicin, azithromycin, tobramycin, amoxicillin, ampicillin and nalidixic acid. Where as the results of in vivo antibiotic trials showed that isolates from both lambs and the kids with diarrhea were susceptible to levofloxacin and ciprofloxacin.

Details

Language :
English
ISSN :
1011-601X
Volume :
30
Issue :
6
Database :
MEDLINE
Journal :
Pakistan journal of pharmaceutical sciences
Publication Type :
Academic Journal
Accession number :
29175799