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Report: Prevalence and antibiotic trials against Salmonella enterica isolated from diarrheic lambs and kids.
- Source :
-
Pakistan journal of pharmaceutical sciences [Pak J Pharm Sci] 2017 Nov; Vol. 30 (6), pp. 2265-2269. - Publication Year :
- 2017
-
Abstract
- Salmonella enterica (S. enterica) is the major zoonotic threat for small ruminants and humans responsible for huge economic losses and high mortality in Pakistan. Lambs and kids of Lahore district were examined to determine the prevalence, hematology and chemotherapy of S. enterica. A total of 200 diarrheic samples (n=100 lambs; n=100 kids) were collected and examined; 59 (29.50%) were found positive for S. enterica. Lambs had lightly greater prevalence (31%) than kids (29%). The frequency analysis (OR=1.16 [reciprocal =0.87]) showed non-significant difference in both the lambs and kids. The significant decrease (Pℜ0.001) in hemoglobin, pack cell volume and total erythrocyte count was observed in infected lambs and kids. Results of in-vitro antibiotic susceptibility test revealed that S. enteric isolated from both lambs and kids were susceptible to levofloxacin, ciprofloxacin, ofloxacin, gentamicin, azithromycin, tobramycin, amoxicillin, ampicillin and nalidixic acid. Where as the results of in vivo antibiotic trials showed that isolates from both lambs and the kids with diarrhea were susceptible to levofloxacin and ciprofloxacin.
- Subjects :
- Animals
Animals, Newborn
Anti-Bacterial Agents adverse effects
Case-Control Studies
Clinical Decision-Making
Diarrhea epidemiology
Diarrhea microbiology
Drug Resistance, Bacterial
Feces microbiology
Humans
Pakistan epidemiology
Predictive Value of Tests
Prevalence
Salmonella enterica isolation & purification
Salmonella enterica pathogenicity
Sheep
Sheep Diseases epidemiology
Sheep Diseases microbiology
Sheep, Domestic
Anti-Bacterial Agents therapeutic use
Diarrhea drug therapy
Diarrhea veterinary
Microbial Sensitivity Tests veterinary
Salmonella enterica drug effects
Sheep Diseases drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1011-601X
- Volume :
- 30
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Pakistan journal of pharmaceutical sciences
- Publication Type :
- Academic Journal
- Accession number :
- 29175799