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Diagnosis of Castleman Disease.

Authors :
Szalat R
Munshi NC
Source :
Hematology/oncology clinics of North America [Hematol Oncol Clin North Am] 2018 Feb; Vol. 32 (1), pp. 53-64.
Publication Year :
2018

Abstract

Castleman disease (CD) is a rare and heterogenous group of disorders sharing in common an abnormal lymph node pathology. CD comprises distinct subtypes with different prognoses. Unicentric CD and multicentric CD are featured by specific systemic manifestations and may be associated with Kaposi sarcoma, non-Hodgkin and Hodgkin lymphoma, and POEMS syndrome. Multicentric CD is classically associated with systemic symptoms and poorer prognosis. In this article, the authors review how to diagnose the disease, keeping in context the clinical findings, biochemical changes and complications associated with CD.<br /> (Copyright © 2017 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1558-1977
Volume :
32
Issue :
1
Database :
MEDLINE
Journal :
Hematology/oncology clinics of North America
Publication Type :
Academic Journal
Accession number :
29157619
Full Text :
https://doi.org/10.1016/j.hoc.2017.09.005