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The Protective Effects of Extra Virgin Olive Oil on Immune-mediated Inflammatory Responses.
- Source :
-
Endocrine, metabolic & immune disorders drug targets [Endocr Metab Immune Disord Drug Targets] 2018; Vol. 18 (1), pp. 23-35. - Publication Year :
- 2018
-
Abstract
- Background and Objective: The increasing interest in the Mediterranean diet (MeDiet) hinges on the relevant role it plays in inflammatory diseases. Several clinical, epidemiological and experimental evidences suggest that consumption of the MeDiet reduces the incidence of certain pathologies related to oxidative stress, chronic inflammation and immune system diseases such as cancer, atherosclerosis and cardiovascular disease (CVD). These reductions can be partially attributed to extra virgin olive oil (EVOO) consumption which has been described as a key bioactive food because of its high nutritional quality and its particular composition of fatty acids, vitamins and polyphenols. Indeed, the beneficial effects of EVOO have been linked to its fatty acid composition, which is very rich in monounsaturated fatty acids (MUFA), and has moderate saturated and polyunsaturated fatty acids (PUFA). The current knowledge available on the beneficial effects of EVOO and its phenolic compounds, specifically its biological properties and antioxidant capacity against immune-mediated inflammatory responses (atherosclerosis, rheumatoid arthritis, diabetes, obesity, cancer, inflammatory bowel disease or neurodegenerative disease, among others) in addition to its potential clinical applications.<br />Conclusion: The increasing body of studies carried out provides compelling evidence that olive polyphenols are potential candidates to combat chronic inflammatory states.<br /> (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.)
- Subjects :
- Animals
Cardiovascular Diseases diet therapy
Cardiovascular Diseases immunology
Cardiovascular Diseases metabolism
Cardiovascular Diseases prevention & control
Humans
Immune System Diseases diet therapy
Immune System Diseases immunology
Immune System Diseases metabolism
Lipid Metabolism
Olive Oil standards
Oxidative Stress
Diet, Mediterranean
Evidence-Based Medicine
Food Quality
Functional Food
Immune System Diseases prevention & control
Immunomodulation
Olive Oil therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 2212-3873
- Volume :
- 18
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Endocrine, metabolic & immune disorders drug targets
- Publication Type :
- Academic Journal
- Accession number :
- 29141575
- Full Text :
- https://doi.org/10.2174/1871530317666171114115632