Efficient Encapsulation of Fluorinated Drugs in the Confined Space of Water-Dispersible Fluorous Supraparticles.

Authors :: Pigliacelli C
Maiolo D
Nonappa
Haataja JS
Amenitsch H
Michelet C
Sánchez Moreno P
Tirotta I
Metrangolo P
Baldelli Bombelli F
Source :: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2017 Dec 18; Vol. 56 (51), pp. 16186-16190. Date of Electronic Publication: 2017 Nov 23.
Publication Year :: 2017
Abstract: Fluorophobic-driven assemblies of gold nanomaterials were stabilized into water-dispersible fluorous supraparticles by the film-forming protein hydrophobin II. The strategy makes use of fluorous nanomaterials of different dimensions to engineer size and inner functionalization of the resulting confined space. The inner fluorous compartments allow efficient encapsulation and transport of high loadings of partially fluorinated drug molecules in water.<br /> (© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Subjects :: Alkynes
Cyclopropanes
Gold chemistry
Halogenation
Macromolecular Substances chemistry
Metal Nanoparticles chemistry
Particle Size
Water chemistry
Benzoxazines chemistry
Celecoxib chemistry
Fluorine chemistry
Leflunomide chemistry

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