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Analysis of a time-delayed mathematical model for tumour growth with an almost periodic supply of external nutrients.

Authors :
Xu S
Bai M
Zhang F
Source :
Journal of biological dynamics [J Biol Dyn] 2017 Dec; Vol. 11 (1), pp. 504-520.
Publication Year :
2017

Abstract

In this paper, the existence, uniqueness and exponential stability of almost periodic solutions for a mathematical model of tumour growth are studied. The establishment of the model is based on the reaction-diffusion dynamics and mass conservation law and is considered with a delay in the cell proliferation process. Using a fixed-point theorem in cones, the existence and uniqueness of almost periodic solutions for different parameter values of the model is proved. Moreover, by the Gronwall inequality, sufficient conditions are established for the exponential stability of the unique almost periodic solution. Results are illustrated by computer simulations.

Details

Language :
English
ISSN :
1751-3766
Volume :
11
Issue :
1
Database :
MEDLINE
Journal :
Journal of biological dynamics
Publication Type :
Academic Journal
Accession number :
29067874
Full Text :
https://doi.org/10.1080/17513758.2017.1386804