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CT-Guided Percutaneous Sclerotherapy for Low-Flow Retrobulbar Intraconal Venous Malformations.
- Source :
-
Cardiovascular and interventional radiology [Cardiovasc Intervent Radiol] 2018 Mar; Vol. 41 (3), pp. 496-501. Date of Electronic Publication: 2017 Oct 24. - Publication Year :
- 2018
-
Abstract
- Background and Aims: Until now, no study has focused exclusively on low-flow retrobulbar intraconal venous malformations (RIVMs) which may require treatment due to cosmetic defect, pain, and visual dysfunction. The treatment for RIVMs which surround the optic nerve remains challenging. This case series aimed to evaluate the technical feasibility, effectiveness, and safety of percutaneous sclerotherapy with polidocanol for low-flow RIVMs, using local anesthesia.<br />Method: This is a prospective, non-comparative, single-center, interventional case series. All patients signed informed consent forms. Seven patients with RIVMs were treated with percutaneous sclerotherapy with polidocanol/air foam using CT guidance. Primary endpoints are reduction in the volume of RIVMs and pain relief assessed by visual analog scale (VAS). Secondary endpoints are exophthalmos and recording adverse events obtained in clinical follow-up during outpatient visits.<br />Results: Results revealed that the mean volume of RIVMs was decreased from 12.05 ± 6.35 cm <superscript>3</superscript> preoperatively to 1.56 ± 0.43 cm <superscript>3</superscript> postoperatively, (p = 0.005), with a mean decrease of 87.05%. The intraocular pressure was decreased from 14.19 ± 2.99 to 11.79 ± 1.25 mmHg, (p = 0.043). The mean VAS score was decreased from 3.43 ± 2.37 preoperatively to 1.29 ± 0.76 postoperatively, (p = 0.023). The exophthalmos score was decreased from 1.75 ± 0.27 to 1.34 ± 0.31 cm, (p = 0.005). All patients were satisfied with the treatment, which did not leave a postoperative scar.<br />Conclusions: The results of percutaneous intralesion injection of polidocanol for RIVMs are encouraging. The present results suggest that this method could be a safe and effective treatment option for patients with RIVMs.
- Subjects :
- Adolescent
Adult
Feasibility Studies
Female
Humans
Male
Middle Aged
Polidocanol
Polyethylene Glycols therapeutic use
Prospective Studies
Sclerosing Solutions therapeutic use
Treatment Outcome
Young Adult
Radiography, Interventional methods
Sclerotherapy methods
Tomography, X-Ray Computed methods
Vascular Malformations therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1432-086X
- Volume :
- 41
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Cardiovascular and interventional radiology
- Publication Type :
- Academic Journal
- Accession number :
- 29067510
- Full Text :
- https://doi.org/10.1007/s00270-017-1822-y