A lignan with glucose uptake activity in 3T3-L1 adipocytes from the stem bark of Knema patentinervia.

Authors :: Taher M
Amiroudine MZAM
Jaffri JM
Amri MS
Susanti D
Abd Hamid S
Rezali MF
Hassan CM
Read RW
Ahmed Q
Ahmad F
Source :: Pakistan journal of pharmaceutical sciences [Pak J Pharm Sci] 2017 Jul; Vol. 30 (4), pp. 1335-1339.
Publication Year :: 2017
Abstract: A new naturally occurring dibenzylbutyrolactone lignan named isocubebinic ether has been isolated from Knema patentinervia. The structure was established by spectroscopic methods, which include Ultraviolet, Infrared, Nuclear Magnetic Resonance and Mass Spectrometry. The compound showed activity in the stimulation of glucose uptake by 3T3-L1 adipocytes.

Subjects :: 3T3 Cells
Animals
Deoxyglucose metabolism
Lignans chemistry
Mice
Molecular Structure
Plant Bark chemistry
Tritium metabolism
Adipocytes metabolism
Glucose metabolism
Lignans pharmacology
Myristicaceae chemistry

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