Favipiravir and Ribavirin Treatment of Epidemiologically Linked Cases of Lassa Fever.

Authors :: Raabe VN
Kann G
Ribner BS
Morales A
Varkey JB
Mehta AK
Lyon GM
Vanairsdale S
Faber K
Becker S
Eickmann M
Strecker T
Brown S
Patel K
De Leuw P
Schuettfort G
Stephan C
Rabenau H
Klena JD
Rollin PE
McElroy A
Ströher U
Nichol S
Kraft CS
Wolf T
Source :: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2017 Sep 01; Vol. 65 (5), pp. 855-859.
Publication Year :: 2017
Abstract: Two patients with Lassa fever are described who are the first human cases treated with a combination of ribavirin and favipiravir. Both patients survived but developed transaminitis and had prolonged detectable virus RNA in blood and semen, suggesting that the possibility of sexual transmission of Lassa virus should be considered.<br /> (© The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.)

Subjects :: Adult
Humans
Lassa virus genetics
Male
Polymerase Chain Reaction
RNA, Viral analysis
RNA, Viral genetics
Togo
Amides therapeutic use
Antiviral Agents therapeutic use
Lassa Fever drug therapy
Lassa Fever physiopathology
Lassa Fever virology
Pyrazines therapeutic use
Ribavirin therapeutic use

Language :: English
ISSN :: 1537-6591
Volume :: 65
Issue :: 5
Database :: MEDLINE
Journal :: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Publication Type :: Academic Journal
Accession number :: 29017278
Full Text :: https://doi.org/10.1093/cid/cix406

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